Single cell molecular alterations reveal target cells and pathways of concussive brain injury

Douglas Arneson; Guanglin Zhang; Zhe Ying; Yumei Zhuang; Hyae Ran Byun; In Sook Ahn; Fernando Gomez-Pinilla; Xia Yang

doi:10.1038/s41467-018-06222-0

Nature Communications (Sep 2018)

Single cell molecular alterations reveal target cells and pathways of concussive brain injury

Douglas Arneson,
Guanglin Zhang,
Zhe Ying,
Yumei Zhuang,
Hyae Ran Byun,
In Sook Ahn,
Fernando Gomez-Pinilla,
Xia Yang

Affiliations

Douglas Arneson: Department of Integrative Biology and Physiology, University of California, Los Angeles
Guanglin Zhang: Department of Integrative Biology and Physiology, University of California, Los Angeles
Zhe Ying: Department of Integrative Biology and Physiology, University of California, Los Angeles
Yumei Zhuang: Department of Integrative Biology and Physiology, University of California, Los Angeles
Hyae Ran Byun: Department of Integrative Biology and Physiology, University of California, Los Angeles
In Sook Ahn: Department of Integrative Biology and Physiology, University of California, Los Angeles
Fernando Gomez-Pinilla: Department of Integrative Biology and Physiology, University of California, Los Angeles
Xia Yang: Department of Integrative Biology and Physiology, University of California, Los Angeles

DOI: https://doi.org/10.1038/s41467-018-06222-0
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 18

Abstract

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Traumatic brain injury (TBI) affects the hippocampus and can lead to neurological and psychiatric disorders. Here, the authors perform single-cell RNA sequencing to reveal molecular pathways across a range of cell types affected during TBI.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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