PREDICTORS OF CORONARY ARTERIES RESTENOSIS AFTER STENTING IN OBESE WOMEN

Abstract

Aim. To study predictors of coronary arteries (CA) restenosis after stenting in women with coronary heart disease (CHD) and obesity.Material and methods. Totally 57 women included (57,1±7,8 y.o.) with CHD: stable angina II-IV functional class and general obesity I-III grade (body mass index — BMI>30 kg/m2) (33,61±2,81 kg/m2), admitted for planned percutaneous intervention (PCI) with CA stenting. Prospective follow-up performed during 1 year after PCI. As resthenosis of CA we mentioned significant (>50%) narrowing of vessel lumen in the area of intervention. All patients underwent laboratory study with assessment of the main and additional metabolic risk factors and EchoCG with measurement of epicardial fat tissue (EFT) thickness.Results. In 35% (n=19) patients the restenosis of CA revealed. The equation of logictic regression was formulated with the most important complex of predictors for resthenosis: the age (standardized regression coefficient SRC=0,7360), insulin (SRC=0,4821), and EFT (SRC=0,4224). The proportion of veritable prediction was 86,6%. The square under ROC-curve was 0,865.Conclusion. The model had been developed may be useful in clinical practice to stratify the risk of complications before planned stenting of CA to improve secondary prevention of CHD.

Keywords

• coronary stenting
• obesity
• restenosis
• risk factors