BMJ Open (May 2022)
Chinese Neonatal Network: a national protocol for collaborative research and quality improvement in neonatal care
- ,
- Chao Chen,
- Li Li,
- Ling Yang,
- Dong Li,
- Hong Jiang,
- Li Ma,
- Jie Yang,
- Shoo K Lee,
- Joseph Ting,
- Qin Zhang,
- Long Li,
- Wenhao Zhou,
- Lili Wang,
- Huayan Zhang,
- Dongmei Chen,
- Yuan Shi,
- Jiangqin Liu,
- Liyan Zhang,
- Deyi Zhuang,
- Bin Yi,
- Zhaoqing Yin,
- Xiuyong Cheng,
- Xiaoying Li,
- Ling Liu,
- Shuping Han,
- Qin Zhou,
- Hui Wu,
- Kun Liang,
- Yun Cao,
- Mingxia Li,
- Mingyan Hei,
- Jianhua Sun,
- Siyuan Jiang,
- Xiaolu Ma,
- Yanchen Wang,
- Huiqing Sun,
- Li-Zhong Du,
- Shoo K. Lee,
- Lizhong Du,
- Falin Xu,
- Xiuying Tian,
- Yong Ji,
- Zhankui Li,
- Xindong Xue,
- Chuanzhong Yang,
- Sannan Wang,
- Xirong Gao,
- Changyi Yang,
- Ruobing Shan,
- Gang Qiu,
- Xinnian Pan,
- Youyan Zhao,
- Wenqing Kang,
- Xuqiang Ye,
- Zhenlang Lin,
- Jiahua Pan,
- Xing Feng,
- Pingyang Chen,
- Yongjun Zhang,
- Jinxing Feng,
- Xinzhu Lin,
- Yinping Qiu,
- Liping Chen,
- Hongxia Song,
- Huiwen Huang,
- Guofang Ding,
- Jimei Wang,
- Qianshen Zhang
Affiliations
- The Royal College of Emergency Medicine, London, London, UK
- Chao Chen
- Gastroenterology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, People`s Republic of China
- Li Li
- 1 Gilead Sciences Inc, Foster City, California, USA
- Ling Yang
- Department of Anatomy and Cell Biology, Fraternal Order of Eagles Diabetes Research Center, Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
- Dong Li
- Hong Jiang
- National Integrated Traditional and Western Medicine Center for Cardiovascular Disease, China-Japan Friendship Hospital, Beijing, China
- Li Ma
- 2 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
- Jie Yang
- Chengdu Xinan Gynecology Hospital, Chengdu, China
- Shoo K Lee
- 2 Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada
- Joseph Ting
- Qin Zhang
- West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China
- Long Li
- 1 Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, Beijing, China
- Wenhao Zhou
- 1 Center for Molecular Medicine, Children`s Hospital of Fudan University, National Children`s Medical Center, Shanghai, China
- Lili Wang
- cardiologist
- Huayan Zhang
- 11 Division of Neonatology and Center for Newborn Care, Guangzhou Women and Children`s Medical Center, Guangzhou, Guangdong, China
- Dongmei Chen
- Department of Neonatology, Quanzhou Maternity and Children’s Hospital, Quanzhou, Fujian Province, China
- Yuan Shi
- Department of Neonatology, Chongqing Medical University Affiliated Children`s Hospital, Chongqing, China
- Jiangqin Liu
- Liyan Zhang
- Department of Pathology, Hebei Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, China
- Deyi Zhuang
- 8 Department of Pediatrics, Xiamen Children`s Hospital, Xiamen, Fujian, China
- Bin Yi
- Zhaoqing Yin
- 10 Department of Neonatology, The People`s Hospital of Dehong, Dehong, Yunnan, China
- Xiuyong Cheng
- Xiaoying Li
- 3 Department of Neonatology, Qilu Children’s Hospital of Shandong University, Jinan, Shandong, China
- Ling Liu
- Department of Ophthalmology, Chongqing Emergency Medical Center; Chongqing University Central Hospital, Chongqing University, Chongqing, China
- Shuping Han
- Qin Zhou
- Epidemiology-Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
- Hui Wu
- Department of Laboratory Medicine, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China
- Kun Liang
- Yun Cao
- 2 Division of Neonatology, Children`s Hospital of Fudan University, National Children`s Medical Center, Shanghai, China
- Mingxia Li
- Mingyan Hei
- 1 Neonatal Center, Beijing Children`s Hospital Capital Medical University, Beijing, China
- Jianhua Sun
- 6 Department of Neonatology, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Siyuan Jiang
- 5 Neonatology, Children’s Hospital of Fudan University, Shanghai, China
- Xiaolu Ma
- 8 Neonatology, The Children’s Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
- Yanchen Wang
- graduate student
- Huiqing Sun
- 9 Division of Neonatology, Children’s Hospital Affiliated to Zhengzhou University, Zhengzhou, China
- Li-Zhong Du
- 13 The Children’s Hospital Zhejiang University School of Medicine, Hangzhou, China
- Shoo K. Lee
- Lizhong Du
- Falin Xu
- Xiuying Tian
- Department of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin, China
- Yong Ji
- Neonatal Intensive Care Unit, Children’s Hospital of Shanxi, Taiyuan, China
- Zhankui Li
- Xindong Xue
- Chuanzhong Yang
- Sannan Wang
- Xirong Gao
- Changyi Yang
- Ruobing Shan
- Gang Qiu
- Xinnian Pan
- 7 Department of Neonatology, Maternal and Child Health Care Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China
- Youyan Zhao
- Wenqing Kang
- 5 Department of Neonatology, Children`s Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, China
- Xuqiang Ye
- Zhenlang Lin
- Jiahua Pan
- Xing Feng
- Pingyang Chen
- Yongjun Zhang
- Jinxing Feng
- Xinzhu Lin
- Yinping Qiu
- Liping Chen
- 4 Department of Neonatology, Jiangxi Provincial Children`s Hospital, Nanchang, Jiangxi, China
- Hongxia Song
- Huiwen Huang
- Guofang Ding
- Jimei Wang
- Qianshen Zhang
- DOI
- https://doi.org/10.1136/bmjopen-2021-051175
- Journal volume & issue
-
Vol. 12,
no. 5
Abstract
Introduction The objective of the Chinese Neonatal Network (CHNN) is to provide a platform for collaborative research, outcomes evaluation and quality improvement for preterm infants with gestational age less than 32 weeks in China. The CHNN is the first national neonatal network and has the largest geographically representative cohort from neonatal intensive care units (NICUs) in China.Methods and analysis Individual-level data from participating NICUs will be collected using a unique database developed by the CHNN on an ongoing basis from January 2019. Data will be prospectively collected from all infants <32 weeks gestation or <1500 g birth weight at 58 participating NICUs. Infant outcomes and inter-institutional variations in outcomes will be examined and used to inform quality improvement measures aimed at improving outcomes. Information about NICU environmental and human resource factors and processes of neonatal care will also be collected and analysed for association with outcomes. Clinical studies, including randomised controlled trials will be conducted using the CHNN data platform.Ethics and dissemination This study was approved by the ethics review board of Children’s Hospital of Fudan University, which was recognised by all participating hospitals. Waiver of consent were granted at all sites. Only non-identifiable patient level data will be transmitted and only aggregate data will be reported in CHNN reports and publications.
