Nature Communications (Jan 2016)
Complex disease and phenotype mapping in the domestic dog
- Jessica J. Hayward,
- Marta G. Castelhano,
- Kyle C. Oliveira,
- Elizabeth Corey,
- Cheryl Balkman,
- Tara L. Baxter,
- Margret L. Casal,
- Sharon A. Center,
- Meiying Fang,
- Susan J. Garrison,
- Sara E. Kalla,
- Pavel Korniliev,
- Michael I. Kotlikoff,
- N. S. Moise,
- Laura M. Shannon,
- Kenneth W. Simpson,
- Nathan B. Sutter,
- Rory J. Todhunter,
- Adam R. Boyko
Affiliations
- Jessica J. Hayward
- Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University
- Marta G. Castelhano
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University
- Kyle C. Oliveira
- Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University
- Elizabeth Corey
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University
- Cheryl Balkman
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University
- Tara L. Baxter
- Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University
- Margret L. Casal
- School of Veterinary Medicine, University of Pennsylvania
- Sharon A. Center
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University
- Meiying Fang
- College of Animal Science and Technology, China Agricultural University
- Susan J. Garrison
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University
- Sara E. Kalla
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University
- Pavel Korniliev
- Department of Biological Statistics and Computational Biology, Cornell University
- Michael I. Kotlikoff
- Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University
- N. S. Moise
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University
- Laura M. Shannon
- Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University
- Kenneth W. Simpson
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University
- Nathan B. Sutter
- Biology Department, La Sierra University
- Rory J. Todhunter
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University
- Adam R. Boyko
- Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University
- DOI
- https://doi.org/10.1038/ncomms10460
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 11
Abstract
The domestic dog is an important model organism for our understanding of cancer and other diseases. Here the authors conduct a genome-wide association study across multiple breeds and identify novel loci significantly associated with several complex diseases and morphological traits.
