696 Single-cell RNA-seq reveals the critical roles of the STING- and MDA5-mediated cytosolic nucleic acid-sensing pathways as well as IFNAR/STAT2 signaling in recombinant MVA-induced antitumor immunity

• Taha Merghoub,
• Ning Yang,
• Liang Deng,
• Tuo Zhang,
• Shuaitong Liu,
• Gregory Mazo,
• Adrian Tan,
• Jiahu Wang,
• John Choi,
• Jenny Zhaoying Xiang

Affiliations

Taha Merghoub

1Memorial Sloan-Kettering Cancer Center, New York, NY, USA

Ning Yang

Aff423 grid.51462.340000000121719952Memorial Sloan Kettering Cancer Center New York NY USA

Liang Deng

Aff425 grid.51462.340000000121719952Department of MedicineMemorial Sloan Kettering Cancer Center New York NY USA

Tuo Zhang

1Weill Cornell Medicine, Houston, TX, USA

Shuaitong Liu

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA

Gregory Mazo

1Memorial Sloan Kettering Cancer Center, New York, NY, United States

Adrian Tan

2Weill Cornell Medical College, New York, NY, United States

Jiahu Wang

3Genvira Biosciences, Ottawa, Canada

John Choi

4IMVAQ Therapeutics, New York, NY, United States

Jenny Zhaoying Xiang

2Weill Cornell Medical College, New York, NY, United States