Escherichia coli Genomic Diversity within Extraintestinal Acute Infections Argues for Adaptive Evolution at Play

Antoine Bridier-Nahmias; Adrien Launay; Alexandre Bleibtreu; Mélanie Magnan; Violaine Walewski; Jérémie Chatel; Sara Dion; Véronique Robbe-Saule; Olivier Clermont; Françoise Norel; Erick Denamur; Olivier Tenaillon

doi:10.1128/mSphere.01176-20

mSphere (Feb 2021)

Escherichia coli Genomic Diversity within Extraintestinal Acute Infections Argues for Adaptive Evolution at Play

Antoine Bridier-Nahmias,
Adrien Launay,
Alexandre Bleibtreu,
Mélanie Magnan,
Violaine Walewski,
Jérémie Chatel,
Sara Dion,
Véronique Robbe-Saule,
Olivier Clermont,
Françoise Norel,
Erick Denamur,
Olivier Tenaillon

Affiliations

Antoine Bridier-Nahmias: ORCiD; Université de Paris, IAME, UMR 1137, INSERM, Paris, France
Adrien Launay: Université de Paris, IAME, UMR 1137, INSERM, Paris, France
Alexandre Bleibtreu: Université de Paris, IAME, UMR 1137, INSERM, Paris, France
Mélanie Magnan: Université de Paris, IAME, UMR 1137, INSERM, Paris, France
Violaine Walewski: Université de Paris, IAME, UMR 1137, INSERM, Paris, France
Jérémie Chatel: Université de Paris, IAME, UMR 1137, INSERM, Paris, France
Sara Dion: Université de Paris, IAME, UMR 1137, INSERM, Paris, France
Véronique Robbe-Saule: Institut Pasteur, Unité de Biochimie des Interactions Macromoléculaires, Paris, France
Olivier Clermont: Université de Paris, IAME, UMR 1137, INSERM, Paris, France
Françoise Norel: Institut Pasteur, Unité de Biochimie des Interactions Macromoléculaires, Paris, France
Erick Denamur: Université de Paris, IAME, UMR 1137, INSERM, Paris, France
Olivier Tenaillon: Université de Paris, IAME, UMR 1137, INSERM, Paris, France

DOI: https://doi.org/10.1128/mSphere.01176-20
Journal volume & issue: Vol. 6, no. 1

Abstract

Read online

Little is known about the dynamics of adaptation in acute bacterial infections. By sequencing multiple isolates from monoclonal extraintestinal Escherichia coli

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

About the journal