Emerging Infectious Diseases (Jun 2024)

Evolution and Antigenic Differentiation of Avian Influenza A(H7N9) Virus, China

  • Yang Liu,
  • Yuhua Chen,
  • Zhiyi Yang,
  • Yaozhong Lin,
  • Siyuan Fu,
  • Junhong Chen,
  • Lingyu Xu,
  • Tengfei Liu,
  • Beibei Niu,
  • Qiuhong Huang,
  • Haixia Liu,
  • Chaofeng Zheng,
  • Ming Liao,
  • Weixin Jia

DOI
https://doi.org/10.3201/eid3006.230530
Journal volume & issue
Vol. 30, no. 6
pp. 1218 – 1222

Abstract

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We characterized the evolution and molecular characteristics of avian influenza A(H7N9) viruses isolated in China during 2021–2023. We systematically analyzed the 10-year evolution of the hemagglutinin gene to determine the evolutionary branch. Our results showed recent antigenic drift, providing crucial clues for updating the H7N9 vaccine and disease prevention and control.

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