Intramolecular substitutions of secondary and tertiary alcohols with chirality transfer by an iron(III) catalyst

Abstract

The direct substitution of the OH group of stereogenic alcohols are reported rarely in literature. Here, the authors demonstrate direct substitution of both secondary and tertiary alcohols with chirality transfer leading to enantioenriched 5-membered, 6-membered and aryl-fused 6-membered heterocyclic compounds.