Platelet microparticles from their features to stroke implication

Abstract

Since 1967 when platelet microparticles were discovered, the platelet’s researchers were demonstrated the procoagulant properties of these platelet membranes nano-fragments. They are versatile bioeffectors in haemostasis because of their membrane receptors content. From these reasons, recently has been suggested that the platelet microparticles may constitute an important marker of atherothrombosis and, consequently a prognosis factor in various vascular diseases, including ischemic stroke. On the other way, the antiplatelet therapy focused on platelet microparticles activity may be beneficial.

Keywords

• microparticles
• platelet activation
• stroke
• atherosclerosis markers