Haematologica (Feb 2007)

New types of MYST3-CBP and CBP-MYST3 fusion transcripts in t(8;16)(p11;p13) acute myeloid leukemias

  • Anne Murati,
  • José Adélaïde,
  • Benoît Quilichini,
  • Virginie Rémy,
  • Danielle Sainty,
  • Anne-Marie Stoppa,
  • Philippe Bernard,
  • Sylviane Olschwang,
  • Daniel Birnbaum,
  • Max Chaffanet,
  • Marie-Joëlle Mozziconacci

DOI
https://doi.org/10.3324/haematol.10744
Journal volume & issue
Vol. 92, no. 2

Abstract

Read online

The t(8;16)(p11;p13) translocation, associated with poor prognosis acute monocytic leukemia, fuses MYST3 on chromosome region 8p11 to CBP on chromosome region 16p13. Two types of MYST3-CBP and CBP-MYST3 fusion transcripts have been identified in patients. We describe two new types of MYST3-CBP transcripts and a new primer set.