Spatiotemporal stop-and-go dynamics of the mitochondrial TOM core complex correlates with channel activity

Affiliations

Shuo Wang: Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart
Lukas Findeisen: Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart
Sebastian Leptihn: Zhejiang University-University of Edinburgh (ZJU-UoE) Institute, Zhejiang University
Mark I. Wallace: Department of Chemistry, King’s College London, Britannia House
Marcel Hörning: Department of Biobased Materials, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart
Stephan Nussberger: Department of Biophysics, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart

Abstract

Wang et al. exploit single-molecule measurements to uncover a potentially new mechanosensitive functionality of mitochondrial TOM core complexes.