Clinical and Translational Allergy (Jan 2020)
Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study
Abstract
Abstract Carboplatin administration can usually be safely continued via a so-called desensitisation protocol when hypersensitivity reactions arise. Severe break-through reactions that occur early during desensitisation are likely to be IgE-mediated; in that case, addition of omalizumab premedication should be strongly considered.
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