Nature Communications (Mar 2022)

cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies

  • Christina Bligaard Pedersen,
  • Søren Helweg Dam,
  • Mike Bogetofte Barnkob,
  • Michael D. Leipold,
  • Noelia Purroy,
  • Laura Z. Rassenti,
  • Thomas J. Kipps,
  • Jennifer Nguyen,
  • James Arthur Lederer,
  • Satyen Harish Gohil,
  • Catherine J. Wu,
  • Lars Rønn Olsen

DOI
https://doi.org/10.1038/s41467-022-29383-5
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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Combining single-cell cytometry datasets increases the analytical flexibility and the statistical power of data analyses. Here, the authors present a method to robustly integrate cytometry data from different batches, experiments, or even different experimental techniques.