Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency

• Oskar Marin-Bejar,
• Damia Romero-Moya,
• Javier Rodriguez-Ubreva,
• Maximiliano Distefano,
• Francesca Lessi,
• Paolo Aretini,
• Alessandro Liquori,
• Julio Castaño,
• Emilia Kozyra,
• Lili Kotmayer,
• Clara Bueno,
• José Cervera,
• José Carlos Rodriguez-Gallego,
• Josep F Nomdedeu,
• Laura Murillo-Sanjuán,
• Cristina Díaz de Heredia,
• Antonio Pérez-Martinez,
• Félix López-Cadenas,
• Carolina Martínez-Laperche,
• Nieves Dorado-Herrero,
• Francisco M Marco,
• Felipe Prósper,
• Pablo Menendez,
• David Valcárcel,
• Esteban Ballestar,
• Csaba Bödör,
• Anna Bigas,
• Albert Catalá,
• Marcin W Wlodarski,
• Alessandra Giorgetti

Affiliations

Oskar Marin-Bejar

Regenerative Medicine Program, Bellvitge Institute for Biomedical Research (IDIBELL) and Program for Clinical Translation of Regenerative Medicine in Catalonia (P-CMRC), Barcelona

Damia Romero-Moya

Regenerative Medicine Program, Bellvitge Institute for Biomedical Research (IDIBELL) and Program for Clinical Translation of Regenerative Medicine in Catalonia (P-CMRC), Barcelona

Javier Rodriguez-Ubreva

Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Barcelona

Maximiliano Distefano

Department of Hematology and Oncology, Institut de Recerca Sant Joan de Déu, Hospital Sant Joan de Déu, Barcelona

Francesca Lessi

Fondazione Pisana Per la Scienza ONLUS (FPS), San Giuliano Terme

Paolo Aretini

Fondazione Pisana Per la Scienza ONLUS (FPS), San Giuliano Terme

Alessandro Liquori

Hematology Research Group, Instituto de Investigación Sanitaria La Fe, Valencia, Spain; Centro de Investigación Biomédica en Red de Oncología (CIBERONC), Instituto de Salud Carlos III, Madrid

Julio Castaño

Advanced and Cell Therapy Services. Banc de Sang i Teixits, Barcelona

Emilia Kozyra

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine; Faculty of Biology, University of Freiburg, Freiburg

Lili Kotmayer

HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University. Budapest, Hungary

Clara Bueno

Josep Carreras Leukaemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona, Barcelona

José Cervera

Hematology Research Group, Instituto de Investigación Sanitaria La Fe, Valencia, Spain; Centro de Investigación Biomédica en Red de Oncología (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain; Genetics Unit, Hospital Universitario y Politécnico La Fe, Valencia

José Carlos Rodriguez-Gallego

Department of Immunology, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System, Las Palmas de Gran Canaria, Spain; Department of Clinical Sciences, University Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain; Department of Medical and Surgical Sciences, School of Medicine, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria

Josep F Nomdedeu

Servei d'Hematologia Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, IIB Sant Pau/Josep Carreras Leukaemia Research Institute (IJC), Barcelona

Laura Murillo-Sanjuán

Pediatric Hematology and Oncology Division, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Barcelona

Cristina Díaz de Heredia

Pediatric Hematology and Oncology Division, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Barcelona

Antonio Pérez-Martinez

Pediatric Department, Universidad Autonoma de Madrid, Madrid, Spain; Hospital La Paz Institute for Health Research, Madrid, Spain; Pediatric Hemato-Oncology Department, University Hospital La Paz, Madrid

Félix López-Cadenas

Servicio de Hematología Hospital Clínico Universitario de Salamanca, salamanca, Spain; Instituto Biosanitario de Salamanca (IBSAL). Salamanca

Carolina Martínez-Laperche

Servicio de Hematología, Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid

Nieves Dorado-Herrero

Servicio de Hematología, Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid

Francisco M Marco

Immunology Department, Dr. Balmis General University Hospital; Institute for Health and Biomedical Research (ISABIAL), Alicante

Felipe Prósper

Centro de Investigación Biomédica en Red de Oncología (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain; Area de Hemato-Oncología, CIMA Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IDISNA), Pamplona, Spain; Servicio de Hematologia, CCUN, Clínica Universidad de Navarra, Universidad de Navarra, Pamplona

Pablo Menendez

Centro de Investigación Biomédica en Red de Oncología (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain; Josep Carreras Leukaemia Research Institute. Department of Biomedicine. School of Medicine, University of Barcelona, Barcelona, Spain; Red Española de Terapias Avanzadas (TERAV) - Instituto de Salud Carlos III, Madrid, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona

David Valcárcel

Servei d’Hematologia, Vall d’Hebron Hospital Universitari; Experimental Hematology, Vall d’Hebron Institute of Oncology (VHIO); Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona

Esteban Ballestar

Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Barcelona, Spain; Epigenetics in Inflammatory and Metabolic Diseases Laboratory, Health Science Center (HSC), East China Normal University (ECNU), Shanghai

Csaba Bödör

HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University. Budapest, Hungary

Anna Bigas

Centro de Investigación Biomédica en Red de Oncología (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain; Programa de Investigación en Cáncer, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain; Josep Carreras Leukaemia Research Institute (IJC), Barcelona

Albert Catalá

Department of Hematology and Oncology, Institut de Recerca Sant Joan de Déu, Hospital Sant Joan de Déu, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Madrid

Marcin W Wlodarski

Department of Hematology, St. Jude Children’s Research Hospital, Memphis, TN

Alessandra Giorgetti

Regenerative Medicine Program, Bellvitge Institute for Biomedical Research (IDIBELL) and Program for Clinical Translation of Regenerative Medicine in Catalonia (P-CMRC), Barcelona, Spain; Fondazione Pisana Per la Scienza ONLUS (FPS), San Giuliano Terme, Italy; Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, Barcelona University, Barcelona