Advanced Ultrasound in Diagnosis and Therapy (Dec 2023)

The Value of VTTQ Combined with B-mode US for Distinguishing Benign from Malignant Breast Masses by Comparing with SE: A Clinical Research

  • Lujing Li, MD, Zuofeng Xu, MD

DOI
https://doi.org/10.37015/AUDT.2023.220041
Journal volume & issue
Vol. 7, no. 4
pp. 394 – 400

Abstract

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Objective The purpose of this study was to compare the diagnostic performance of virtual touch tissue quantification (VTTQ) combined with B-mode ultrasonograpgy (US), strain elastography (SE) combined with B-mode US and B-mode US alone in differentiating the properties of breast lesions. Methods A retrospective database was queried for 283 healthy subjects and 100 consecutive patients with 130 breast lesions. All the cases were examined by B-mode US, VTTQ and SE. Histological diagnosis was used as the reference standard. The area under the receiver operating curve (AUC) values of each data set was compared.Results Twenty-two lesions were determined as malignant and 108 as benign. The best cutoff point of VTTQ was 7.82 m/s. The AUC of B-mode US combined with VTTQ or SE was greater than that of B-mode US alone (0.913 or 0.918 vs. 0.797) (P = 0.007 and 0.012).Conclusion Both VTTQ and SE could give help to B-mode US in distinguishing benign from malignant breast lesions about elastography values. There was no difference between them.

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