Molecules (Nov 2010)

Platycoside N: A New Oleanane-Type Triterpenoid Saponin from the Roots of Platycodon grandiflorum

  • Jing Zhang,
  • Li Chen,
  • Ying-Ping Wang,
  • Yi-Nan Zheng,
  • Wei Li,
  • Zi Wang,
  • Lan Xiang,
  • Wei Zhang

DOI
https://doi.org/10.3390/molecules15128702
Journal volume & issue
Vol. 15, no. 12
pp. 8702 – 8708

Abstract

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A new oleanane-type triterpenoid saponin, named platycoside N (1), together with six known saponins, was isolated from the roots of Platycodon grandiflorum. On the basis of acid hydrolysis, comprehensive spectroscopic data analyses and comparison with the spectral data of the known compounds, its structure was elucidated as 3-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-28-oic acid 28-O-β-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside. The six known compounds were platycodin D (2), deapioplatycodin D (3), platycodin D3 (4), deapio- platycodin D3 (5), platycoside E (6) and deapioplatycoside E (7).

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