Molecules (May 2008)

Synthesis of an ent-Halimanolide from ent-Halimic Acid

  • Julio G. Urones,
  • Faustino Mollinedo,
  • David Díez,
  • Pilar Basabe,
  • Rosalina F. Moro,
  • Almudena Conde,
  • Isidro S. Marcos

DOI
https://doi.org/10.3390/molecules13051120
Journal volume & issue
Vol. 13, no. 5
pp. 1120 – 1134

Abstract

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An efficient synthesis of ent-halimanolide 2 (15,16-epoxy-12-oxo-ent-halima- 5(10),13(16),14-trien-18,2β-olide), from ent-halimic acid has been achieved, corroborating the structure of the natural compound and establishing its absolute configuration.

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