Predicting survival of cancer patients by chromosomal copy number heterogeneity

Abstract

We recently introduced a method to derive intra-tumor heterogeneity (ITH) from a single copy number measurement. This method stratifies patients for survival and could potentially help to identify low and high-risk patients with clinical relevance.

Keywords

• biomarker
• intra-tumor heterogeneity
• chromosomal instability
• pan-cancer