Modern methods of the treatment of hereditary epidermolysis bullosa

Abstract

Today there are no ethiopathogenetic treatment methods for treating hereditary epidermolysis bullosa. All available treatment methods are symptomatic and are mainly aimed at patient care. Since severe forms of hereditary epidermolysis bullosa affect multiple organs, patients need assistance of both dermatologists and skilled experts such as general practitioners (pediatricians), gastroenterologists and dentists or ophthalmologists, surgeons, hematologists, oncologists, etc. when needed. To take efficient therapeutic and preventive measures, clinical recommendations and treatment standards are needed. Promising therapeutic methods (protein replacement, cell and gene techniques) are currently at different development and implementation stages but they can solve problems related to the treatment of hereditary epidermolysis bullosa in the future.

Keywords

• врожденный буллезный эпидермолиз
• перевязочные средства
• раневые повязки
• генная терапия
• заместительная белковая терапия
• клеточная терапия
• аллогенные фибробласты
• стволовые клетки
• hereditary epidermolysis bullosa
• dressings
• wound dressings
• gene therapy
• protein replacement therapy
• cell therapy
• allogenous fibroblasts
• stem cells