Advances in adeno-associated virus mediated gene therapy in tumors

Abstract

Adeno-associated virus (AAV) is a human parvovirus with defects and no disease.AAV vector, as an ideal carrier for the transduction of target genes, has certain advantages in long-term gene correction and gene therapy by transferring foreign bases into cells by using the virus's capacity to infect cells.Due to its advantages of extensive host, strong safety and continuous expression of foreign genes, AAV has been used in gene therapy for a variety of tumor.

Keywords

• aav|vectors|gene therapy|tumor