Communications Biology (Jan 2023)

Zyxin regulates embryonic stem cell fate by modulating mechanical and biochemical signaling interface

  • Songjing Zhang,
  • Lor Huai Chong,
  • Jessie Yong Xing Woon,
  • Theng Xuan Chua,
  • Elsie Cheruba,
  • Ai Kia Yip,
  • Hoi-Yeung Li,
  • Keng-Hwee Chiam,
  • Cheng-Gee Koh

DOI
https://doi.org/10.1038/s42003-023-04421-0
Journal volume & issue
Vol. 6, no. 1
pp. 1 – 15

Abstract

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Zyxin regulates mouse embryonic stem cell differentiation by integrating mechanical cues through actin stress fibres and focal adhesions and biochemical cues through YAP signalling.