Nature Communications (Mar 2023)

Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents

  • Adrian E. Desai Boström,
  • Peter Andersson,
  • Mathias Rask-Andersen,
  • Håkan Jarbin,
  • Johan Lundberg,
  • Jussi Jokinen

DOI
https://doi.org/10.1038/s41467-023-36973-4
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 8

Abstract

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There are conflicting results on the effectiveness of pharmacologic interventions for suicide prevention in adolescence. Here, the authors show, in a retrospective registry study from Sweden during 2016–2020, that regional utilization rates of clozapine, electroconvulsive therapy and lithium in 15–19-year-olds were associated with lower excess suicide death rates in male adolescents