Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia

Lauren N. Miterko; Tao Lin; Joy Zhou; Meike E. van der Heijden; Jaclyn Beckinghausen; Joshua J. White; Roy V. Sillitoe

doi:10.1038/s41467-021-21417-8

Nature Communications (Feb 2021)

Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia

Lauren N. Miterko,
Tao Lin,
Joy Zhou,
Meike E. van der Heijden,
Jaclyn Beckinghausen,
Joshua J. White,
Roy V. Sillitoe

Affiliations

Lauren N. Miterko: Department of Pathology and Immunology, Baylor College of Medicine
Tao Lin: Department of Pathology and Immunology, Baylor College of Medicine
Joy Zhou: Department of Pathology and Immunology, Baylor College of Medicine
Meike E. van der Heijden: Department of Pathology and Immunology, Baylor College of Medicine
Jaclyn Beckinghausen: Department of Pathology and Immunology, Baylor College of Medicine
Joshua J. White: Department of Pathology and Immunology, Baylor College of Medicine
Roy V. Sillitoe: Department of Pathology and Immunology, Baylor College of Medicine

DOI: https://doi.org/10.1038/s41467-021-21417-8
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 16

Abstract

Read online

Deep brain stimulation (DBS) has potential for several movement disorders. Here the authors show that DBS improves motor function in a mouse model of ataxia.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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