Frontiers in Public Health (Dec 2022)
Spatial-temporal clustering of an outbreak of SARS-CoV-2 Delta VOC in Guangzhou, China in 2021
- Qian Zhang,
- Qian Zhang,
- Meng Zhang,
- Meng Zhang,
- Jianxiong Hu,
- Guanhao He,
- Yan Zhou,
- Yan Zhou,
- Xuguang Chen,
- Xuguang Chen,
- Yali Zhuang,
- Yali Zhuang,
- Zuhua Rong,
- Lihua Yin,
- Jianguo Zhao,
- Zitong Huang,
- Zitong Huang,
- Weilin Zeng,
- Xing Li,
- Zhihua Zhu,
- Yerong Tang,
- Yerong Tang,
- Yi Quan,
- Yi Quan,
- Yihan Li,
- Yihan Li,
- Li Zhang,
- Li Zhang,
- Di Fu,
- Yan Li,
- Yan Li,
- Jianpeng Xiao
Affiliations
- Qian Zhang
- School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China
- Qian Zhang
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Meng Zhang
- Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Meng Zhang
- Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangzhou, China
- Jianxiong Hu
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Guanhao He
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Yan Zhou
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Yan Zhou
- School of Public Health, Southern Medical University, Guangzhou, China
- Xuguang Chen
- Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Xuguang Chen
- Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangzhou, China
- Yali Zhuang
- Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Yali Zhuang
- Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangzhou, China
- Zuhua Rong
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Lihua Yin
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Jianguo Zhao
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Zitong Huang
- Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Zitong Huang
- School of Public Health, Sun Yat-sen University, Guangzhou, China
- Weilin Zeng
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Xing Li
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Zhihua Zhu
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Yerong Tang
- School of Public Health, Sun Yat-sen University, Guangzhou, China
- Yerong Tang
- Arboviral Disease Prevention Department, Yunnan Institute of Parasitic Diseases, Puer, China
- Yi Quan
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Yi Quan
- School of Public Health, Southern Medical University, Guangzhou, China
- Yihan Li
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Yihan Li
- School of Public Health, Southern Medical University, Guangzhou, China
- Li Zhang
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Li Zhang
- School of Public Health, Southern Medical University, Guangzhou, China
- Di Fu
- Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China
- Yan Li
- Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- Yan Li
- Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Guangzhou, China
- Jianpeng Xiao
- Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China
- DOI
- https://doi.org/10.3389/fpubh.2022.1050096
- Journal volume & issue
-
Vol. 10
Abstract
BackgroundIn May 2021, the SARS-CoV-2 Delta variant led to the first local outbreak in China in Guangzhou City. We explored the epidemiological characteristics and spatial-temporal clustering of this outbreak.MethodsBased on the 153 cases in the SARS-CoV-2 Delta variant outbreak, the Knox test was used to analyze the spatial-temporal clustering of the outbreak. We further explored the spatial-temporal clustering by gender and age groups, as well as compared the changes of clustering strength (S) value between the two outbreaks in Guangzhou.ResultsThe result of the Knox analysis showed that the areas at short distances and brief periods presented a relatively high risk. The strength of clustering of male-male pairs was higher. Age groups showed that clustering was concentrated in cases aged ≤ 18 years matched to 18–59 years and cases aged 60+ years. The strength of clustering of the outbreak declined after the implementation of public health measures. The change of strength of clustering at time intervals of 1–5 days decreased greater in 2021 (S = 129.19, change rate 38.87%) than that in 2020 (S = 83.81, change rate 30.02%).ConclusionsThe outbreak of SARS-CoV-2 Delta VOC in Guangzhou has obvious spatial-temporal clustering. The timely intervention measures are essential role to contain this outbreak of high transmission.
Keywords
