Scientific Reports (Mar 2024)

A multimodal submillimeter MRI atlas of the human cerebellum

  • Wenjiao Lyu,
  • Ye Wu,
  • Khoi Minh Huynh,
  • Sahar Ahmad,
  • Pew-Thian Yap

DOI
https://doi.org/10.1038/s41598-024-55412-y
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 15

Abstract

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Abstract The human cerebellum is engaged in a broad array of tasks related to motor coordination, cognition, language, attention, memory, and emotional regulation. A detailed cerebellar atlas can facilitate the investigation of the structural and functional organization of the cerebellum. However, existing cerebellar atlases are typically limited to a single imaging modality with insufficient characterization of tissue properties. Here, we introduce a multifaceted cerebellar atlas based on high-resolution multimodal MRI, facilitating the understanding of the neurodevelopment and neurodegeneration of the cerebellum based on cortical morphology, tissue microstructure, and intra-cerebellar and cerebello-cerebral connectivity.