Communications Medicine (Nov 2021)
A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies
- Patthara Kongsuphol,
- Huan Jia,
- Hoi Lok Cheng,
- Yue Gu,
- Bhuvaneshwari D/O Shunmuganathan,
- Ming Wei Chen,
- Sing Mei Lim,
- Say Yong Ng,
- Paul Ananth Tambyah,
- Haziq Nasir,
- Xiaohong Gao,
- Dousabel Tay,
- Seunghyeon Kim,
- Rashi Gupta,
- Xinlei Qian,
- Mary M. Kozma,
- Kiren Purushotorman,
- Megan E. McBee,
- Paul A. MacAry,
- Hadley D. Sikes,
- Peter R. Preiser
Affiliations
- Patthara Kongsuphol
- Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART)
- Huan Jia
- Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART)
- Hoi Lok Cheng
- Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART)
- Yue Gu
- Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore (NUS)
- Bhuvaneshwari D/O Shunmuganathan
- Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore (NUS)
- Ming Wei Chen
- School of Biological Science (SBS), Nanyang Technological University (NTU)
- Sing Mei Lim
- Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART)
- Say Yong Ng
- Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART)
- Paul Ananth Tambyah
- Department of Medicine, National University Hospital (NUH)
- Haziq Nasir
- Department of Medicine, National University Hospital (NUH)
- Xiaohong Gao
- School of Biological Science (SBS), Nanyang Technological University (NTU)
- Dousabel Tay
- Department of Chemical Engineering, Massachusetts Institute of Technology (MIT)
- Seunghyeon Kim
- Department of Chemical Engineering, Massachusetts Institute of Technology (MIT)
- Rashi Gupta
- Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore (NUS)
- Xinlei Qian
- Life Sciences Institute (LSI), National University of Singapore (NUS), Center for Life Sciences
- Mary M. Kozma
- Life Sciences Institute (LSI), National University of Singapore (NUS), Center for Life Sciences
- Kiren Purushotorman
- Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore (NUS)
- Megan E. McBee
- Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART)
- Paul A. MacAry
- Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore (NUS)
- Hadley D. Sikes
- Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART)
- Peter R. Preiser
- Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART)
- DOI
- https://doi.org/10.1038/s43856-021-00045-9
- Journal volume & issue
-
Vol. 1,
no. 1
pp. 1 – 12
Abstract
Kongsuphol et al. develop a paper-based, vertical flow assay to detect SARS-CoV-2 neutralizing antibodies. The point-of-care assay has comparable performance to lab-based tests and provides results in 10 min.
