Physicochemical characterization tungsten oxide modified hydroxyapatite embedded into polylactic acid nanocomposite for biomedical applications

Muteb H. Alshammari; Ahmed Onayzan Alshammari; Mohamed Tharwat Elabbasy; Rafat Zreiq; M.A. El-Morsy; A.A. Menazea; M.F.H. Abd El-Kader

Results in Physics (Jun 2023)

Physicochemical characterization tungsten oxide modified hydroxyapatite embedded into polylactic acid nanocomposite for biomedical applications

Muteb H. Alshammari,
Ahmed Onayzan Alshammari,
Mohamed Tharwat Elabbasy,
Rafat Zreiq,
M.A. El-Morsy,
A.A. Menazea,
M.F.H. Abd El-Kader

Affiliations

Muteb H. Alshammari: Department of Health Informatics, College of Public Health and Health informatics. University of Ha'il, Ha'il, Saudi Arabia
Ahmed Onayzan Alshammari: Department of Surgery, College of Medicine, University of Ha'il, Ha'il, Saudi Arabia
Mohamed Tharwat Elabbasy: Department of Public Health, College of Public Health and Health Informatics, Ha'il University, Ha’il 2440, Saudi Arabia; Food Control Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt
Rafat Zreiq: Department of Public Health, College of Public Health and Health Informatics, Ha'il University, Ha’il 2440, Saudi Arabia; Applied Science Research Center, Applied Science Private University, Amman, Jordan
M.A. El-Morsy: College of Science and Humanities in Al-Kharj, Physics Department, Plasma Technology and Material Science Unit, Prince Sattam Bin Abdulaziz University, Al-kharj 11942, Saudi Arabia; Physics Department, Faculty of Science, University of Damietta, New Damietta 34517, Egypt; Corresponding author at: College of Science and Humanities in Al-Kharj, Physics Department, Plasma Technology and Material Science Unit, Prince Sattam Bin Abdulaziz University, Al-kharj 11942, Saudi Arabia.
A.A. Menazea: Spectroscopy Department, Physics Research Institute, National Research Centre, Dokki, 12622 Giza, Egypt
M.F.H. Abd El-Kader: Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt

Journal volume & issue: Vol. 49
p. 106446

Abstract

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To compensate for the feeble antimicrobial potential of hydroxyapatite (HAp), the compound has been incorporated into different nanocomposites (NCs) in addition to powder and fibrous structure. Hydroxyapatite (HAp)/tungsten oxide/graphene oxide (GO) ternary nanocomposite introduces a significant enhance in the cell viability to 96.7 ± 3% towards the osteoblast cells. The chemical compositions were approved by various analytical techniques such as XRD, FTIR, XPS, and EDS. TEM shows well-defined, rod-like HAp grains. The triple ingredient HAp/WO3/GO nano-composite exhibits an 22.8 nm grain size. FESEM introduces grain shape deviation via changing HAp additives from semi-spherical to needle-like with macro-porous structure within the composite of HAp/WO3/GO. Moreover, compatibility of ternary nanocomposite inside the PLA environment led to decrease in the contact angle of the nanofibrous structure reached 16.5 ± 4.4°. The combination of HAp and organic/inorganic elements might represent a good characterization for the target biological applications. HAp/WO3/GO composite exhibits a significant improvement in anti-microbial activity to be around 85.6 ± 1.6 % and 110.1 ± 2.0 % in for E. coli and S. aureus.

Published in Results in Physics

ISSN: 2211-3797 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Physics
Website: http://www.journals.elsevier.com/results-in-physics/

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