Journal of Clinical Medicine (May 2022)
Antithrombotic Therapy in Elderly Patients with Acute Coronary Syndromes
- Clara Bonanad,
- Francisca Esteve-Claramunt,
- Sergio García-Blas,
- Ana Ayesta,
- Pablo Díez-Villanueva,
- Jose-Ángel Pérez-Rivera,
- José Luis Ferreiro,
- Joaquim Cánoves,
- Francisco López-Fornás,
- Albert Ariza Solé,
- Sergio Raposerias,
- David Vivas,
- Regina Blanco,
- Daznia Bompart Berroterán,
- Alberto Cordero,
- Julio Núñez,
- Lorenzo Fácila,
- Iván J. Núñez-Gil,
- José Luis Górriz,
- Vicente Bodí,
- Manuel Martínez-Selles,
- Juan Miguel Ruiz Nodar,
- Francisco Javier Chorro
Affiliations
- Clara Bonanad
- Cardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain
- Francisca Esteve-Claramunt
- Department of Nursing, Faculty of Health Sciences, European University of Valencia, 46010 Valencia, Spain
- Sergio García-Blas
- Cardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain
- Ana Ayesta
- Cardiology Department, Central University Hospital of Asturias, 33011 Oviedo, Spain
- Pablo Díez-Villanueva
- Cardiology Department, La Princesa University Hospital, 28006 Madrid, Spain
- Jose-Ángel Pérez-Rivera
- Cardiology Department, University Hospital of Burgos, Isabel I University, 09003 Burgos, Spain
- José Luis Ferreiro
- Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain
- Joaquim Cánoves
- Cardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain
- Francisco López-Fornás
- Cardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain
- Albert Ariza Solé
- Cardiology Department, University Hospital of Burgos, Isabel I University, 09003 Burgos, Spain
- Sergio Raposerias
- Cardiology Department, Álvaro Cunqueiro University Hospital, 36213 Vigo, Spain
- David Vivas
- Department of Medicine, Cardiovascular Institute, San Carlos University Hospital, Complutense University, 28040 Madrid, Spain
- Regina Blanco
- Cardiology Department, Quirónsalud Hospital of Valencia, 46010 Valencia, Spain
- Daznia Bompart Berroterán
- Department of Medicine, University of Valencia, 46010 Valencia, Spain
- Alberto Cordero
- Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain
- Julio Núñez
- Cardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain
- Lorenzo Fácila
- Cardiology Department, General University Hospital of Valencia, 46014 Valencia, Spain
- Iván J. Núñez-Gil
- Department of Medicine, Cardiovascular Institute, San Carlos University Hospital, Complutense University, 28040 Madrid, Spain
- José Luis Górriz
- INCLIVA Biomedical Research Institute, 46010 Valencia, Spain
- Vicente Bodí
- Cardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain
- Manuel Martínez-Selles
- Cardiology Department, Hospital Universitario Gregorio Marañón, Universidad Europea, Complutense University, 28040 Madrid, Spain
- Juan Miguel Ruiz Nodar
- Servicio de Cardiología, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante ISABIAL, CIBER-CV, 03010 Alicante, Spain
- Francisco Javier Chorro
- Cardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain
- DOI
- https://doi.org/10.3390/jcm11113008
- Journal volume & issue
-
Vol. 11,
no. 11
p. 3008
Abstract
The treatment of acute coronary syndrome (ACS) in elderly patients continues to be a challenge because of the characteS.G.B.ristics of this population and the lack of data and specific recommendations. This review summarizes the current evidence about critical points of oral antithrombotic therapy in elderly patients. To this end, we discuss the peculiarities and differences reported referring to dual antiplatelet therapy (DAPT) in ACS management in elderly patients and what might be the best option considering these population characteristics. Furthermore, we analyze antithrombotic strategies in patients with atrial fibrillation (AF), with a particular focus on those cases that also present coronary artery disease (CAD). It is imperative to deepen our knowledge regarding the management of these challenging patients through real-world data and specifically designed geriatric studies to help resolve the questions remaining in their disease management.
Keywords
