Nature Communications (May 2022)
Combining rapid antigen testing and syndromic surveillance improves community-based COVID-19 detection in a low-income country
- Fergus J. Chadwick,
- Jessica Clark,
- Shayan Chowdhury,
- Tasnuva Chowdhury,
- David J. Pascall,
- Yacob Haddou,
- Joanna Andrecka,
- Mikolaj Kundegorski,
- Craig Wilkie,
- Eric Brum,
- Tahmina Shirin,
- A. S. M. Alamgir,
- Mahbubur Rahman,
- Ahmed Nawsher Alam,
- Farzana Khan,
- Ben Swallow,
- Frances S. Mair,
- Janine Illian,
- Caroline L. Trotter,
- Davina L. Hill,
- Dirk Husmeier,
- Jason Matthiopoulos,
- Katie Hampson,
- Ayesha Sania
Affiliations
- Fergus J. Chadwick
- Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow
- Jessica Clark
- Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow
- Shayan Chowdhury
- a2i, United Nations Development Program, ICT Ministry
- Tasnuva Chowdhury
- Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow
- David J. Pascall
- MRC Biostatistics Unit, University of Cambridge
- Yacob Haddou
- Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow
- Joanna Andrecka
- Food and Agriculture Organisation of the United Nations in support of the UN Interagency Support Team
- Mikolaj Kundegorski
- COVID-19 in LMICs Research Group, University of Glasgow
- Craig Wilkie
- COVID-19 in LMICs Research Group, University of Glasgow
- Eric Brum
- Food and Agriculture Organisation of the United Nations in support of the UN Interagency Support Team
- Tahmina Shirin
- Institute of Epidemiology, Disease Control and Research, Ministry of Health
- A. S. M. Alamgir
- Institute of Epidemiology, Disease Control and Research, Ministry of Health
- Mahbubur Rahman
- Institute of Epidemiology, Disease Control and Research, Ministry of Health
- Ahmed Nawsher Alam
- Institute of Epidemiology, Disease Control and Research, Ministry of Health
- Farzana Khan
- Institute of Epidemiology, Disease Control and Research, Ministry of Health
- Ben Swallow
- COVID-19 in LMICs Research Group, University of Glasgow
- Frances S. Mair
- General Practice and Primary Care, Institute of Health and Wellbeing, University of Glasgow
- Janine Illian
- COVID-19 in LMICs Research Group, University of Glasgow
- Caroline L. Trotter
- Departments of Pathology and Veterinary Medicine, University of Cambridge
- Davina L. Hill
- Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow
- Dirk Husmeier
- School of Mathematics and Statistics, University of Glasgow
- Jason Matthiopoulos
- Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow
- Katie Hampson
- Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow
- Ayesha Sania
- Division of Developmental Neuroscience, Department of Psychiatry, Columbia University
- DOI
- https://doi.org/10.1038/s41467-022-30640-w
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 9
Abstract
Rapid antigen tests and syndromic surveillance for identification of COVID-19 cases are limited by low sensitivity and specificity, respectively. Here, the authors use data from Bangladesh and show that combining the two methods improves diagnostic accuracy in a range of epidemiological scenarios.
