A case of congenital afibrinogenemia with multiple thrombotic and hemorrhagic disorders

Abstract

Abstract This is a case of congenital afibrinogenemia with multiple thrombotic and hemorrhagic events. His fibrinogen concentration was negatively correlated with thrombin time and prothrombin time and abnormally negatively correlated with plasma D‐dimer levels. The individualized standard for fibrinogen concentration may help to balance thrombotic and hemorrhagic events for this disease.

Keywords

• congenital afibrinogenemia
• fibrinogen infusion
• hemorrhagic complication
• individualized treatment
• thrombotic complication