Nature Communications (Mar 2020)

Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling

  • Melinda Liu Perkins,
  • Dirk Benzinger,
  • Murat Arcak,
  • Mustafa Khammash

DOI
https://doi.org/10.1038/s41467-020-15166-3
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.