Medicina (Jul 2021)

Advancements in Transcatheter Aortic Valve Implantation: A Focused Update

  • Niccolò Ciardetti,
  • Francesca Ciatti,
  • Giulia Nardi,
  • Francesca Maria Di Muro,
  • Pierluigi Demola,
  • Edoardo Sottili,
  • Miroslava Stolcova,
  • Francesca Ristalli,
  • Alessio Mattesini,
  • Francesco Meucci,
  • Carlo Di Mario

DOI
https://doi.org/10.3390/medicina57070711
Journal volume & issue
Vol. 57, no. 7
p. 711

Abstract

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Transcatheter aortic valve implantation (TAVI) has become the leading technique for aortic valve replacement in symptomatic patients with severe aortic stenosis with conventional surgical aortic valve replacement (SAVR) now limited to patients younger than 65–75 years due to a combination of unsuitable anatomies (calcified raphae in bicuspid valves, coexistent aneurysm of the ascending aorta) and concerns on the absence of long-term data on TAVI durability. This incredible rise is linked to technological evolutions combined with increased operator experience, which led to procedural refinements and, accordingly, to better outcomes. The article describes the main and newest technical improvements, allowing an extension of the indications (valve-in-valve procedures, intravascular lithotripsy for severely calcified iliac vessels), and a reduction of complications (stroke, pacemaker implantation, aortic regurgitation).

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