Prevalence of Secondary Hyperparathyroidism in Hemo- Dialysis Patients

Abstract

Introduction: One persistent complication of chronic kidney disease is secondary hyperparathyroidism. Early diagnosis of this disease will reduce morbidity in patients undergoing hemodialysis. Aims & Objectives: To determine the prevalence of secondary hyperparathyroidism in chronic kidney disease patients at National Institute of Kidney Diseases, SZH Lahore. Place and Duration of Study: A cross sectional study was conducted at Nephrology Department of Shaikh Zayed Hospital (SZH) Lahore after getting approval from Institutional Review Board of National Health Research Complex (NHRC). It was conducted from September 2023 to November 2023 &140 hemo-dialysis patients were selected. Material & Methods: We measured serum parathyroid hormone, hemoglobin and other variables, at Biochemistry laboratory of Sheikh Zayed Hospital, in 140 hemodialysis patients. Serum samples were measured for PTH levels using ELISA method. The data was analyzed using SPSS version 20.P value ? 0.05 was considered significant. Results: Fifteen patients had secondary hyperparathyroidism out of 140 hemodialysis patients. Hyperparathyroidism was observed in 10.71 % of the patients. Hyperparathyroidism patients had significantly low calcium, hemoglobin levels & higher phosphate levels. Conclusion: The prevalence of secondary hyperparathyroidism is low at 10.71% of patients undergoing hemodialysis at National Institute of Kidney Disease, SZH Lahore.

Keywords

• Chronic kidney disease
• hemo-dialysis
• parathyroid hormone
• Secondary hyperparathyroidism