Crystal structure of 3-benzyl-1-[(1,2,3,4-tetrahydronaphthalen-1-ylidene)amino]thiourea

Abstract

In the title compound, C18H19N3S, the dihedral angle between the planes of the benzene rings is 58.63 (8)°. The six-membered ring bonded to the thiosemicarbazide group (r.m.s. deviation = 0.038 Å) adopts a sofa conformation, with one of the methylene-group C atoms as the flap. A short intramolecular N—H...N contact is observed. In the crystal, molecules are linked by weak N—H...S interactions to generate C(4) chains propagating in the [010] direction, with adjacent molecules related by glide symmetry.

Keywords

• crystal structure
• thiosemicarabazides
• antiproliferative agents