One versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway

Fabrice Jean-Pierre; Arsh Vyas; Thomas H. Hampton; Michael A. Henson; George A. O’Toole

doi:10.1128/mBio.00006-21

mBio (Apr 2021)

One versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway

Fabrice Jean-Pierre,
Arsh Vyas,
Thomas H. Hampton,
Michael A. Henson,
George A. O’Toole

Affiliations

Fabrice Jean-Pierre: Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA
Arsh Vyas: Department of Chemical Engineering, University of Massachusetts, Amherst, Massachusetts, USA
Thomas H. Hampton: Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA
Michael A. Henson: Department of Chemical Engineering, University of Massachusetts, Amherst, Massachusetts, USA
George A. O’Toole: ORCiD; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA

DOI: https://doi.org/10.1128/mBio.00006-21
Journal volume & issue: Vol. 12, no. 2

Abstract

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Culture-independent studies have revealed that chronic lung infections in persons with cystic fibrosis (pwCF) are rarely limited to one microbial species. Interactions among bacterial members of these polymicrobial communities in the airways of pwCF have been reported to modulate clinically relevant phenotypes.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal