Splenic Marginal Zone Lymphoma: A Case with Long History

Abstract

Splenic Marginal Zone Lymphoma (SMZL) is a rare, indolent B-cell Non-Hodgkin Lymphoma (NHL) which may present with isolated splenomegaly. Herein, we report a case of SMZL in a 48 years old male with asymptomatic pancytopenia and insidious development of massive splenomegaly over a period of 11 years, where splenectomy not only revealed the diagnosis of SMZL after bone marrow biopsy was non-diagnostic, but also resulted in normalisation of blood counts without any further treatment.

Keywords

• non-hodgkin lymphoma
• pancytopenia
• splenomegaly