Brazilian Journal of Nephrology (Mar 2015)

Contrast-induced nephropathy after computed tomography

  • Luciano da Silva Selistre,
  • Vandréa Carla de Souza,
  • Laurence Dubourg,
  • Mário Bernardes Wagner,
  • João Rubião Hoefel Filho,
  • David Saitovitch

DOI
https://doi.org/10.5935/0101-2800.20150005
Journal volume & issue
Vol. 37, no. 1
pp. 27 – 31

Abstract

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Introduction: Contrast induced nephropathy is the third most prevalent preventable cause of acute kidney injury in hospitalized patients. It defined as an absolute increase in serum creatinine ≥ 0.5 mg/dL and relative ≥ 25% increase. Objective: We studied the risk factors to intravenous injection contrast nephropathy after computed tomography. Methods: We studied 400 patients prospectively. Results: The incidence of contrast induced nephropathy, with an absolute or a relative increase were 4.0% and 13.9%, respectively. Diabetes and cardiac failure were independent risk factors for CIN a relative increase de serum creatinine (O.R.: 3.5 [95% CI: 1.92-6.36], p < 0.01, 2.61 [95% CI: 1.14-6.03%], p < 0.05, respectively). Conclusions: We showed association between uses of intravenous injection contrast after computed tomography with acute injury renal, notably with diabetes and heart failure.

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