Absence of Telomerase Activity in Malignant Bone Tumors and Soft-Tissue
Sarcomas

Nina K. Lauer; Sandra M. Maier; Martin Oberringer; Michael Schulte; Wolf Mutschler; Rainer G. Hanselmann; Manfred Schartl; Stefan J. Scherer; Reiner J. Wirbel

doi:10.1080/13577140220127549

Sarcoma (Jan 2002)

Absence of Telomerase Activity in Malignant Bone Tumors and Soft-Tissue Sarcomas

Nina K. Lauer,
Sandra M. Maier,
Martin Oberringer,
Michael Schulte,
Wolf Mutschler,
Rainer G. Hanselmann,
Manfred Schartl,
Stefan J. Scherer,
Reiner J. Wirbel

Affiliations

Nina K. Lauer: Department of Reconstructive Surgery, University of Saarland, Homburg/Saar D-66421, Germany
Sandra M. Maier: Department of Human Genetics, University of Saarland, Geb. 68, Homburg/Saar D-66421, Germany
Martin Oberringer: Department of Experimental Physics, University of Saarland, Geb. 22, Saarbrücken 68111, Germany
Michael Schulte: Department of Experimental Physics, University of Saarland, Geb. 22, Saarbrücken 68111, Germany
Wolf Mutschler: Department of Surgery, Ludwig Maximillian-University of Munich, Klinikum Innenstadt, Munich 80336, Germany
Rainer G. Hanselmann: Department of Experimental Physics, University of Saarland, Geb. 22, Saarbrücken 68111, Germany
Manfred Schartl: Department of Physiological Chemistry I, Biocenter, University of Wuerzburg, Wuerzburg 97074, Germany
Stefan J. Scherer: Department of Physiological Chemistry I, Biocenter, University of Wuerzburg, Wuerzburg 97074, Germany
Reiner J. Wirbel: Department of Surgery, Elisabeth-Hospital, Neuwied 56564, Germany

DOI: https://doi.org/10.1080/13577140220127549
Journal volume & issue: Vol. 6, no. 1
pp. 43 – 46

Abstract

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Purpose: Telomerase activity appears to play a crucial role in the development of many tumors. More than 80% of all malignant human tumors show an increased telomerase activity. However, conflicting results have been reported about telomerase activity in sarcomas. The aim of the study was to obtain more information about telomerase activity in sarcomas based on a large number of cases.

Published in Sarcoma

ISSN: 1357-714X (Print); 1369-1643 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://onlinelibrary.wiley.com/journal/5805

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