Marine Drugs (May 2017)

The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

  • Samuel D. Robinson,
  • Qing Li,
  • Aiping Lu,
  • Pradip K. Bandyopadhyay,
  • Mark Yandell,
  • Baldomero M. Olivera,
  • Helena Safavi-Hemami

DOI
https://doi.org/10.3390/md15050145
Journal volume & issue
Vol. 15, no. 5
p. 145

Abstract

Read online

The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species’ conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts.

Keywords