Nature Communications (Aug 2021)

Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses

  • Natalia Ortega,
  • Marta Ribes,
  • Marta Vidal,
  • Rocío Rubio,
  • Ruth Aguilar,
  • Sarah Williams,
  • Diana Barrios,
  • Selena Alonso,
  • Pablo Hernández-Luis,
  • Robert A. Mitchell,
  • Chenjerai Jairoce,
  • Angeline Cruz,
  • Alfons Jimenez,
  • Rebeca Santano,
  • Susana Méndez,
  • Montserrat Lamoglia,
  • Neus Rosell,
  • Anna Llupià,
  • Laura Puyol,
  • Jordi Chi,
  • Natalia Rodrigo Melero,
  • Daniel Parras,
  • Pau Serra,
  • Edwards Pradenas,
  • Benjamin Trinité,
  • Julià Blanco,
  • Alfredo Mayor,
  • Sonia Barroso,
  • Pilar Varela,
  • Anna Vilella,
  • Antoni Trilla,
  • Pere Santamaria,
  • Carlo Carolis,
  • Marta Tortajada,
  • Luis Izquierdo,
  • Ana Angulo,
  • Pablo Engel,
  • Alberto L. García-Basteiro,
  • Gemma Moncunill,
  • Carlota Dobaño

DOI
https://doi.org/10.1038/s41467-021-24979-9
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 10

Abstract

Read online

Long-term characterisation of SARS-CoV-2 antibody kinetics is needed to understand the protective role of the immune response. Here the authors describe antibody levels and neutralisation activity in healthcare workers over seven months and investigate the role of immunity to endemic human coronaviruses.