Metal- and light-free approach to polyheterocycles via a quinone-Cs2CO3 couple promoted regioselective cascade radical cyclization

Qijing Zhang; Pan Yue; Hao Lei; Cong-Ying Zhou; Chengming Wang

Green Synthesis and Catalysis (Aug 2024)

Metal- and light-free approach to polyheterocycles via a quinone-Cs2CO3 couple promoted regioselective cascade radical cyclization

Qijing Zhang,
Pan Yue,
Hao Lei,
Cong-Ying Zhou,
Chengming Wang

Affiliations

Qijing Zhang: College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou 511443, China
Pan Yue: College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou 511443, China
Hao Lei: Corresponding authors.; College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou 511443, China
Cong-Ying Zhou: Corresponding authors.; College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou 511443, China
Chengming Wang: Corresponding authors.; College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou 511443, China

Journal volume & issue: Vol. 5, no. 3
pp. 195 – 199

Abstract

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A highly efficient, transition-metal- and light-free approach to polyheterocycles via regioselective cascade radical cyclization is developed. The redox-neutral protocol has a broad substrate scope with good functional group tolerance and probably undergoes a SET process, which is initiated by catalytic amounts of quinone in combination with 2.0 equiv. of Cs2CO3.

Published in Green Synthesis and Catalysis

ISSN: 2666-5549 (Online)
Publisher: KeAi Communications Co. Ltd.
Country of publisher: China
LCC subjects: Technology: Chemical technology; Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.keaipublishing.com/en/journals/green-synthesis-and-catalysis/

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