Evaluation of Zenian and Avishan-e Shirazi Antibacterial Activity against Vibrio cholerae Strains

Abstract

Background: The aim of this study was to determine the antibacterial activity of Zataria multiflora Boiss (Avishan-e Shirazi) and Carum copticum (Zenian) extracts on Vibrio cholerae American Type Culture Collection (ATCC14035)and V. cholerae Persian Type Culture Collection (PTCC1611) strains. Methods: Antimicrobial effects of the extracts were assayed by disc diffusion and broth microdilution methods. Results: Using susceptibility tests, it was shown that Carum copticum methanolic extract had the highest antibacterial effect on V. cholerae standard strains at 6.25 mg/ml concentration. Conclusions: Other evaluations considering herbal extracts as an antibacterial agent as well as in vivo examination of these extracts is needed to provide a natural, cost effective and strong alternative for traditionally less effective antibiotics normally used.

Keywords

• Zataria Multiflora
• Boiss Carum
• Copticum Vibrio cholerae