Combination therapy of low-fluence photodynamic therapy and intravitreal ranibizumab for choroidal neovascular membrane in choroidal osteoma

Abstract

Choroidal osteoma is an unusual form of intraocular calcification seen in otherwise healthy eyes. It is a benign idiopathic osseous tumor of the choroid, typically seen in young females. Choroidal neovascular membrane (CNVM) is a complication seen in one-third of these patients and carries a poor visual outcome. We report a case of a 25-year-old hyperthyroid female with choroidal osteoma and subfoveal CNVM in her left eye which was successfully treated using low-fluence photodynamic therapy (PDT) with verteporfin followed by a single injection of intravitreal ranibizumab.

Keywords

• Pediatric traumatic cataract
• primary posterior capsulotomy
• posterior capsule opacification
• square-edge intraocular lens
• visual axis opacification
• Multifocal electroretinogram
• principal components′
• analysis
• retinitis pigmentosa
• Behcet′s disease
• HLA-B51
• optical coherence tomography
• macular hole
• Graves′ ophthalmopathy
• thyroid eye disease
• unilateral
• Assam
• corneal ulcer
• fusarium
• mycotic keratitis
• Antifungal sensitivity testing
• amphotericin B
• Aspergillus
• fungal keratitis
• polymerase chain reaction--single-stranded conformational polymorphism.
• Lid coloboma
• limbal dermoid
• nasopalpebral lipoma-coloboma syndrome
• Bilateral
• breast metastasis
• extraocular muscle
• Conventional dacryocystorhinostomy
• trans-canalicular laser-assisted dacryocystorhinostomy
• Eye surgery
• operation theater
• parental presence
• squint surgery
• witnessing a surgery
• Centrocecal visual field defect
• cilioretinal artery occlusion
• fluorescein angiogram
• intranasal cocaine
• Caesarean section
• epidural anesthesia
• Horner′s syndrome
• Acute myeloid leukemia
• hypopyon
• masquerade syndrome
• Low-fluence photodynamic therapy
• choroidal neovascular membrane
• choroidal osteoma
• ranibizumab