The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk loci

Abstract

Glioma is a highly malignant brain tumor with a grim prognosis. Genetic factors play a role in glioma development. While some susceptibility loci associated with glioma have been identified, the risk loci associated with prognosis have received less attention. This study aims to identify risk loci associated with glioma prognosis and establish a prognostic prediction model for glioma patients in the Chinese Han population.

Keywords

• glioma prognosis
• gwas
• risk loci
• prognostic prediction model
• lasso cox regression
• nomogram