The role of genetic testing in the prognosis and management of solid tumors. A literature review

Abstract

Introduction: Cancer is the leading cause of death and an important impediment to increasing life expectancy in every country of the world. During the process of oncogenesis, genetic and epigenetic changes lead to abnormal expression of genes associated with cellular pathways that coordinate extremely important functions such as cell multiplication, cell differentiation, cell death, and cell cycle.

Keywords

• literature review
• oncogenetics
• personalized therapies
• molecular marker
• cancer classification