Pharmaceutics (Feb 2024)

Niosomes: Composition, Formulation Techniques, and Recent Progress as Delivery Systems in Cancer Therapy

  • Sergio Liga,
  • Cristina Paul,
  • Elena-Alina Moacă,
  • Francisc Péter

DOI
https://doi.org/10.3390/pharmaceutics16020223
Journal volume & issue
Vol. 16, no. 2
p. 223

Abstract

Read online

Niosomes are vesicular nanocarriers, biodegradable, relatively non-toxic, stable, and inexpensive, that provide an alternative for lipid-solid carriers (e.g., liposomes). Niosomes may resolve issues related to the instability, fast degradation, bioavailability, and insolubility of different drugs or natural compounds. Niosomes can be very efficient potential systems for the specific delivery of anticancer, antioxidant, anti-inflammatory, antimicrobial, and antibacterial molecules. This review aims to present an overview of their composition, the most common formulation techniques, as well as of recent utilizations as delivery systems in cancer therapy.

Keywords