EXPERIMENTAL MODELING OF FROSTBITES OF VARYING SEVERITY IN LABORATORY ANIMALS. PART 2. MORPHOLOGICAL ASSESSMENT OF THE EFFECTIVENESS OF THE DEVICE FOR SIMULATING CONTACT FROSTBITE

Abstract

Background. The study of new methods of treating frostbite is feasible using an experimental model, the effectiveness of which is confirmed by morphological results. Purpose of the study. Morphological substantiation of the effectiveness of the developed device for simulating contact frostbites of varying severity. Material and methods. In 30 laboratory rats, the designed device was used to simulate cold trauma of varying severity. The material for morphological research was collected at different time intervals. Results. Morphological argumentation of the effectiveness of the created device for reproducing both superficial and deep frostbites is presented. Conclusions. The developed device is not difficult to manufacture; it is safe and allows reproducing standardized contact frostbites of varying severity in laboratory animals.

Keywords

• device
• frostbite
• morphology
• experiment
• rats