Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1

Sebastian Jojoa-Cruz; Kei Saotome; Che Chun Alex Tsui; Wen-Hsin Lee; Mark S. P. Sansom; Swetha E. Murthy; Ardem Patapoutian; Andrew B. Ward

doi:10.1038/s41467-022-28511-5

Nature Communications (Feb 2022)

Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1

Sebastian Jojoa-Cruz,
Kei Saotome,
Che Chun Alex Tsui,
Wen-Hsin Lee,
Mark S. P. Sansom,
Swetha E. Murthy,
Ardem Patapoutian,
Andrew B. Ward

Affiliations

Sebastian Jojoa-Cruz: Department of Integrative Structural and Computational Biology, Scripps Research
Kei Saotome: Department of Integrative Structural and Computational Biology, Scripps Research
Che Chun Alex Tsui: Department of Integrative Structural and Computational Biology, Scripps Research
Wen-Hsin Lee: Department of Integrative Structural and Computational Biology, Scripps Research
Mark S. P. Sansom: Department of Biochemistry, University of Oxford
Swetha E. Murthy: Howard Hughes Medical Institute, Department of Neuroscience, Dorris Neuroscience Center, Scripps Research
Ardem Patapoutian: Howard Hughes Medical Institute, Department of Neuroscience, Dorris Neuroscience Center, Scripps Research
Andrew B. Ward: Department of Integrative Structural and Computational Biology, Scripps Research

DOI: https://doi.org/10.1038/s41467-022-28511-5
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 11

Abstract

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Flycatcher1 (FLYC1) is a candidate mechanosensitive channel involved in Venus flytrap touch-induced prey capture. Here, the authors report structural and functional details of FLYC1, with insights into gating conformational transitions.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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