Brain commissures and related pathologies

Abstract

White matter commissural fibers are a special type of fibers that connect similar areas of the cortex of opposite hemispheres. Telencephalic commissures have a direct impact on cognitive function. Diencephalic commissures connect the structures of the midbrain, diencephalon, and forebrain. The pathways they form are involved in the proliferation of white matter diseases. The review provides updated information on the morphology, functions, impairments of development and blood supply of brain commissures and their functional relationship with neurological diseases such as Alzheimer's disease, Parino's syndrome, agenesis of the corpus callosum, and autism spectrum disorders.

Keywords

• commissural fibers
• corpus callosum
• anterior commissure
• posterior commissure
• fornix
• habenular commissure
• massa intermedia
• neurodegenerative diseases