Design and Evaluation of Pyridinyl Sulfonyl Piperazine LpxH Inhibitors with Potent Antibiotic Activity Against Enterobacterales
Amanda F. Ennis,
C. Skyler Cochrane,
Patrick A. Dome,
Pyeonghwa Jeong,
Jincheng Yu,
Hyejin Lee,
Carly S. Williams,
Yang Ha,
Weitao Yang,
Pei Zhou,
Jiyong Hong
Affiliations
Amanda F. Ennis
Department of Chemistry, Duke University, Durham, North Carolina, United States
C. Skyler Cochrane
Department of Chemistry, Duke University, Durham, North Carolina, United States
Patrick A. Dome
Department of Chemistry, Duke University, Durham, North Carolina, United States
Pyeonghwa Jeong
Department of Chemistry, Duke University, Durham, North Carolina, United States
Jincheng Yu
Department of Chemistry, Duke University, Durham, North Carolina, United States
Hyejin Lee
Department of Chemistry, Duke University, Durham, North Carolina, United States
Carly S. Williams
Department of Biochemistry, Duke University School of Medicine, Durham, North Carolina, United States
Yang Ha
Berkeley Center for Structural Biology, Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, California, United States
Weitao Yang
Department of Chemistry, Duke University, Durham, North Carolina, United States
Pei Zhou
Department of Chemistry, Duke University, Durham, North Carolina, United States
Jiyong Hong
Department of Chemistry, Duke University, Durham, North Carolina, United States
